There's a release of norepinephrine from the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors within the dorsal horn to lessen afferent pain transmission and develop analgesia. Therefore, medication like clonidine that goal alpha-2 receptors can impact the transmission of suffering. Clonidine treats substantial hypertension by stimulating αtwo receptors https://sparxsocial.com/story10282304/the-single-best-strategy-to-use-for-onolidine